Production of NOS2 and inflammatory cytokines is reduced by selected protein kinase inhibitors with partial repolarization of HL-60 derived and human blood macrophages

JAK/STAT pathway plays a well-known role in macrophage polarization, but other signaling routes may also be involved. The aim of this study was to identify new signaling pathways and repolarize macrophages by selected protein kinase inhibitors. HL-60 derived macrophages were chosen as model cells an...

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Detalles Bibliográficos
Autores principales: Bögel, Gábor, Murányi, József, Szokol, Bálint, Kukor, Zoltán, Móra, István, Kardon, Tamás, Őrfi, László, Hrabák, András
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741463/
https://www.ncbi.nlm.nih.gov/pubmed/35028455
http://dx.doi.org/10.1016/j.heliyon.2021.e08670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741463/
https://www.ncbi.nlm.nih.gov/pubmed/35028455
http://dx.doi.org/10.1016/j.heliyon.2021.e08670

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