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Total body proton and heavy-ion irradiation causes cellular senescence and promotes pro-osteoclastogenic activity in mouse bone marrow

Low-LET photon radiation-induced persistent alterations in bone marrow (BM) cells are well documented in total-body irradiated (TBI) rodents and also among radiotherapy patients. However, the late effects of protons and high-LET heavy-ion radiation on BM cells and its implications in osteoclastogene...

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Detalles Bibliográficos
Autores principales: Kumar, Kamendra, Datta, Kamal, Fornace, Albert J., Suman, Shubhankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741516/
https://www.ncbi.nlm.nih.gov/pubmed/35028468
http://dx.doi.org/10.1016/j.heliyon.2021.e08691