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Adverse Events of Thiopurine Therapy in Pediatric Inflammatory Bowel Disease and Correlations with Metabolites: A Cohort Study

BACKGROUND: In the recent era of growing availability of biological agents, the role of thiopurines needs to be reassessed with the focus on toxicity. AIMS: We assessed the incidence and predictive factors of thiopurine-induced adverse events (AE) resulting in therapy cessation in pediatric inflamma...

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Detalles Bibliográficos
Autores principales: Jagt, Jasmijn Z., Pothof, Christine D., Buiter, Hans J. C., van Limbergen, Johan E., van Wijk, Michiel P., Benninga, Marc A., de Boer, Nanne K. H., de Meij, Tim G. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741678/
https://www.ncbi.nlm.nih.gov/pubmed/33532972
http://dx.doi.org/10.1007/s10620-021-06836-3