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Adverse Events of Thiopurine Therapy in Pediatric Inflammatory Bowel Disease and Correlations with Metabolites: A Cohort Study
BACKGROUND: In the recent era of growing availability of biological agents, the role of thiopurines needs to be reassessed with the focus on toxicity. AIMS: We assessed the incidence and predictive factors of thiopurine-induced adverse events (AE) resulting in therapy cessation in pediatric inflamma...
Autores principales: | Jagt, Jasmijn Z., Pothof, Christine D., Buiter, Hans J. C., van Limbergen, Johan E., van Wijk, Michiel P., Benninga, Marc A., de Boer, Nanne K. H., de Meij, Tim G. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741678/ https://www.ncbi.nlm.nih.gov/pubmed/33532972 http://dx.doi.org/10.1007/s10620-021-06836-3 |
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