New insights into the molecular mechanism of rhodopsin retinitis pigmentosa from the biochemical and functional characterization of G90V, Y102H and I307N mutations

Mutations in the photoreceptor protein rhodopsin are known as one of the leading causes of retinal degeneration in humans. Two rhodopsin mutations, Y102H and I307N, obtained in chemically mutagenized mice, are currently the subject of increased interest as relevant models for studying the process of...

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Detalles Bibliográficos
Autores principales: Herrera-Hernández, María Guadalupe, Razzaghi, Neda, Fernandez-Gonzalez, Pol, Bosch-Presegué, Laia, Vila-Julià, Guillem, Pérez, Juan Jesús, Garriga, Pere
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741697/
https://www.ncbi.nlm.nih.gov/pubmed/34997336
http://dx.doi.org/10.1007/s00018-021-04086-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741697/
https://www.ncbi.nlm.nih.gov/pubmed/34997336
http://dx.doi.org/10.1007/s00018-021-04086-0

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