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Genomic studies controvert the existence of the CUX1 p75 isoform

CUX1, encoding a homeodomain-containing transcription factor, is recurrently deleted or mutated in multiple tumor types. In myeloid neoplasms, CUX1 deletion or mutation carries a poor prognosis. We have previously established that CUX1 functions as a tumor suppressor in hematopoietic cells across mu...

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Detalles Bibliográficos
Autores principales: Krishnan, Manisha, Senagolage, Madhavi D., Baeten, Jeremy T., Wolfgeher, Donald J., Khan, Saira, Kron, Stephen J., McNerney, Megan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741762/
https://www.ncbi.nlm.nih.gov/pubmed/34997000
http://dx.doi.org/10.1038/s41598-021-03930-4