Cargando…

Regulation of gene expression by the APP family in the adult cerebral cortex

Amyloid precursor protein (APP) is associated with both familial and sporadic forms of Alzheimer’s disease. APP has two homologs, amyloid precursor-like protein 1 and 2 (APLP1 and APLP2), and they have functional redundancy. APP intracellular c-terminal domain (AICD), produced by sequential α- or β-...

Descripción completa

Detalles Bibliográficos
Autores principales: Cha, Hye Ji, Shen, Jie, Kang, Jongkyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741778/
https://www.ncbi.nlm.nih.gov/pubmed/34997052
http://dx.doi.org/10.1038/s41598-021-04027-8