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Transcriptomes of peripheral blood mononuclear cells from juvenile dermatomyositis patients show elevated inflammation even when clinically inactive

In juvenile dermatomyositis (JDM), the most common pediatric inflammatory myopathy, weakness is accompanied by a characteristic rash that often becomes chronic and is associated with vascular damage. We hoped to understand the molecular underpinnings of JDM, particularly when untreated, which would...

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Detalles Bibliográficos
Autores principales: Roberson, Elisha D. O., Mesa, Rosana A., Morgan, Gabrielle A., Cao, Li, Marin, Wilfredo, Pachman, Lauren M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741808/
https://www.ncbi.nlm.nih.gov/pubmed/34997119
http://dx.doi.org/10.1038/s41598-021-04302-8