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Calculating the force-dependent unbinding rate of biological macromolecular bonds from force-ramp optical trapping assays
The non-covalent biological bonds that constitute protein–protein or protein–ligand interactions play crucial roles in many cellular functions, including mitosis, motility, and cell–cell adhesion. The effect of external force ([Formula: see text] ) on the unbinding rate ([Formula: see text] ) of mac...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741823/ https://www.ncbi.nlm.nih.gov/pubmed/34996945 http://dx.doi.org/10.1038/s41598-021-03690-1 |