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Calculating the force-dependent unbinding rate of biological macromolecular bonds from force-ramp optical trapping assays

The non-covalent biological bonds that constitute protein–protein or protein–ligand interactions play crucial roles in many cellular functions, including mitosis, motility, and cell–cell adhesion. The effect of external force ([Formula: see text] ) on the unbinding rate ([Formula: see text] ) of mac...

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Detalles Bibliográficos
Autores principales: Paul, Apurba, Alper, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741823/
https://www.ncbi.nlm.nih.gov/pubmed/34996945
http://dx.doi.org/10.1038/s41598-021-03690-1

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