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Rocaglamide promotes the infiltration and antitumor immunity of NK cells by activating cGAS-STING signaling in non-small cell lung cancer

Background: Natural killer (NK) cell-based immunotherapy is clinically limited due to insufficient tumor infiltration in solid tumors. We have previously found that the natural product rocaglamide (RocA) can enhance NK cell-mediated killing of non-small cell lung cancer (NSCLC) cells by inhibiting a...

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Detalles Bibliográficos
Autores principales: Yan, Xuewei, Yao, Chao, Fang, Cheng, Han, Min, Gong, Chenyuan, Hu, Dan, Shen, Weiming, Wang, Lixin, Li, Suyun, Zhu, Shiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741839/
https://www.ncbi.nlm.nih.gov/pubmed/35002511
http://dx.doi.org/10.7150/ijbs.65019