Insights into the critical role of the PXR in preventing carcinogenesis and chemotherapeutic drug resistance

Pregnane x receptor (PXR) as a nuclear receptor is well-established in drug metabolism, however, it has pleiotropic functions in regulating inflammatory responses, glucose metabolism, and protects normal cells against carcinogenesis. Most studies focus on its transcriptional regulation, however, PXR...

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Detalles Bibliográficos
Autores principales: Niu, Xiaxia, Wu, Ting, Li, Gege, Gu, Xinsheng, Tian, Yanan, Cui, Hongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741843/
https://www.ncbi.nlm.nih.gov/pubmed/35002522
http://dx.doi.org/10.7150/ijbs.68724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741843/
https://www.ncbi.nlm.nih.gov/pubmed/35002522
http://dx.doi.org/10.7150/ijbs.68724

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