Sequential allogeneic transplantation and ruxolitinib maintenance for a synchronous PCM1‐JAK2 positive myeloid sarcoma and acute B‐lymphoblastic leukemia

The translocation t(8;9)(p22;p24) results in the production of a chimeric PCM1‐JAK2 fusion protein leading to the constitutive activation of the Janus Kinase 2 that renders this disease potentially sensitive to ruxolitinib. Here, we report an interesting case of PCM1‐JAK2 myeloproliferative neoplasm...

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Detalles Bibliográficos
Autores principales: Rizzuto, Giuliana, Leoncin, Matteo, Imbergamo, Silvia, Taurino, Daniela, Mico, Maria Caterina, Tosi, Manuela, Michelato, Anna, Buklijas, Ksenija, Spinelli, Orietta, Lussana, Federico, Lessi, Federica, Pizzi, Marco, Bonaldi, Laura, Binotto, Gianni, Rambaldi, Alessandro, Gurrieri, Carmela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741870/
https://www.ncbi.nlm.nih.gov/pubmed/35028141
http://dx.doi.org/10.1002/ccr3.5212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741870/
https://www.ncbi.nlm.nih.gov/pubmed/35028141
http://dx.doi.org/10.1002/ccr3.5212

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