High BRCA1 gene expression increases the risk of early distant metastasis in ER(+) breast cancers

Although the function of the BRCA1 gene has been extensively studied, the relationship between BRCA1 gene expression and tumor aggressiveness remains controversial in sporadic breast cancers. Because the BRCA1 protein is known to regulate estrogen signaling, we selected microarray data of ER(+) brea...

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Detalles Bibliográficos
Autores principales: Chang, Hui-Ju, Yang, Ueng-Cheng, Lai, Mei-Yu, Chen, Chen-Hsin, Fann, Yang-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741892/
https://www.ncbi.nlm.nih.gov/pubmed/34996912
http://dx.doi.org/10.1038/s41598-021-03471-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741892/
https://www.ncbi.nlm.nih.gov/pubmed/34996912
http://dx.doi.org/10.1038/s41598-021-03471-w

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