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High BRCA1 gene expression increases the risk of early distant metastasis in ER(+) breast cancers
Although the function of the BRCA1 gene has been extensively studied, the relationship between BRCA1 gene expression and tumor aggressiveness remains controversial in sporadic breast cancers. Because the BRCA1 protein is known to regulate estrogen signaling, we selected microarray data of ER(+) brea...
Autores principales: | Chang, Hui-Ju, Yang, Ueng-Cheng, Lai, Mei-Yu, Chen, Chen-Hsin, Fann, Yang-Cheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741892/ https://www.ncbi.nlm.nih.gov/pubmed/34996912 http://dx.doi.org/10.1038/s41598-021-03471-w |
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