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Human IgE does not bind to human FcRn

The neonatal Fc receptor (FcRn) is known to mediate placental transfer of IgG from mother to unborn. IgE is widely known for triggering immune responses to environmental antigens. Recent evidence suggests FcRn-mediated transplacental passage of IgE during pregnancy. However, direct interaction of Fc...

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Detalles Bibliográficos
Autores principales: Brinkhaus, Maximilian, van der Kooi, Elvera J., Bentlage, Arthur E. H., Ooijevaar-de Heer, Pleuni, Derksen, Ninotska I. L., Rispens, Theo, Vidarsson, Gestur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741920/
https://www.ncbi.nlm.nih.gov/pubmed/34996950
http://dx.doi.org/10.1038/s41598-021-03852-1