Cargando…
Human IgE does not bind to human FcRn
The neonatal Fc receptor (FcRn) is known to mediate placental transfer of IgG from mother to unborn. IgE is widely known for triggering immune responses to environmental antigens. Recent evidence suggests FcRn-mediated transplacental passage of IgE during pregnancy. However, direct interaction of Fc...
Autores principales: | Brinkhaus, Maximilian, van der Kooi, Elvera J., Bentlage, Arthur E. H., Ooijevaar-de Heer, Pleuni, Derksen, Ninotska I. L., Rispens, Theo, Vidarsson, Gestur |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741920/ https://www.ncbi.nlm.nih.gov/pubmed/34996950 http://dx.doi.org/10.1038/s41598-021-03852-1 |
Ejemplares similares
-
The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement
por: Brinkhaus, Maximilian, et al.
Publicado: (2022) -
Reduced FcRn-mediated transcytosis of IgG2 due to a missing Glycine in its lower hinge
por: Stapleton, Nigel M., et al.
Publicado: (2019) -
Characterization of the Rabbit Neonatal Fc Receptor (FcRn) and Analyzing the Immunophenotype of the Transgenic Rabbits That Overexpresses FcRn
por: Catunda Lemos, Ana Paula, et al.
Publicado: (2012) -
The Role of FcRn in Antigen Presentation
por: Baker, Kristi, et al.
Publicado: (2014) -
Room temperature structure of human IgG4-Fc from crystals analysed in situ
por: Davies, Anna M., et al.
Publicado: (2017)