Calpain-mediated protein targets in cardiac mitochondria following ischemia–reperfusion

Calpain 1 and 2 (CPN1/2) are calcium-dependent cysteine proteases that exist in cytosol and mitochondria. Pharmacologic inhibition of CPN1/2 decreases cardiac injury during ischemia (ISC)–reperfusion (REP) by improving mitochondrial function. However, the protein targets of CPN1/2 activation during...

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Detalles Bibliográficos
Autores principales: Li, Ling, Thompson, Jeremy, Hu, Ying, Lesnefsky, Edward J., Willard, Belinda, Chen, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741987/
https://www.ncbi.nlm.nih.gov/pubmed/34997008
http://dx.doi.org/10.1038/s41598-021-03947-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741987/
https://www.ncbi.nlm.nih.gov/pubmed/34997008
http://dx.doi.org/10.1038/s41598-021-03947-9

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