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A computational modeling approach for dosing endoscopic intratumoral chemotherapy for advanced non-small cell lung cancer

We recently developed a computational model of cisplatin pharmacodynamics in an endobronchial lung tumor following ultrasound-guided transbronchial needle injection (EBUS-TBNI). The model suggests that it is more efficacious to apportion the cisplatin dose between injections at different sites rathe...

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Detalles Bibliográficos
Autores principales: Mori, Vitor, Bates, Jason H. T., Jantz, Michael, Mehta, Hiren J., Kinsey, C. Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8741990/
https://www.ncbi.nlm.nih.gov/pubmed/34996946
http://dx.doi.org/10.1038/s41598-021-03849-w