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A novel graph convolutional neural network for predicting interaction sites on protein kinase inhibitors in phosphorylation
Protein kinase-inhibitor interactions are key to the phosphorylation of proteins involved in cell proliferation, differentiation, and apoptosis, which shows the importance of binding mechanism research and kinase inhibitor design. In this study, a novel machine learning module (i.e., the WL Box) was...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742007/ https://www.ncbi.nlm.nih.gov/pubmed/34997142 http://dx.doi.org/10.1038/s41598-021-04230-7 |