The rexinoid V-125 reduces tumor growth in preclinical models of breast and lung cancer

Rexinoids are ligands which activate retinoid X receptors (RXRs), regulating transcription of genes involved in cancer-relevant processes. Rexinoids have anti-neoplastic activity in multiple preclinical studies. Bexarotene, used to treat cutaneous T cell lymphoma, is the only FDA-approved rexinoid....

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Detalles Bibliográficos
Autores principales: Reich, Lyndsey A., Moerland, Jessica A., Leal, Ana S., Zhang, Di, Carapellucci, Sarah, Lockwood, Beth, Jurutka, Peter W., Marshall, Pamela A., Wagner, Carl E., Liby, Karen T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742020/
https://www.ncbi.nlm.nih.gov/pubmed/34997154
http://dx.doi.org/10.1038/s41598-021-04415-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742020/
https://www.ncbi.nlm.nih.gov/pubmed/34997154
http://dx.doi.org/10.1038/s41598-021-04415-0

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