BIRC2–BIRC3 amplification: a potentially druggable feature of a subset of head and neck cancers in patients with Fanconi anemia

Head-and-neck squamous cell carcinomas (HNSCCs) are relatively common in patients with Fanconi anemia (FA), a hereditary chromosomal instability disorder. Standard chemo-radiation therapy is not tolerated in FA due to an overall somatic hypersensitivity to such treatment. The question is how to find...

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Detalles Bibliográficos
Autores principales: Roohollahi, Khashayar, de Jong, Yvonne, Pai, Govind, Zaini, Mohamad Amr, de Lint, Klaas, Sie, Daoud, Rooimans, Martin A., Rockx, Davy, Hoskins, Elizabeth E., Ameziane, Najim, Wolthuis, Rob, Joenje, Hans, Wells, Susanne I., Dorsman, Josephine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742043/
https://www.ncbi.nlm.nih.gov/pubmed/34997070
http://dx.doi.org/10.1038/s41598-021-04042-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742043/
https://www.ncbi.nlm.nih.gov/pubmed/34997070
http://dx.doi.org/10.1038/s41598-021-04042-9

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