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O-ring-induced transverse aortic constriction (OTAC) is a new simple method to develop cardiac hypertrophy and heart failure in mice

Suture-based transverse aortic constriction (TAC) in mice is one of the most frequently used experimental models for cardiac pressure overload-induced heart failure. However, the incidence of heart failure in the conventional TAC depends on the operator’s skill. To optimize and simplify this method,...

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Detalles Bibliográficos
Autores principales: Nakao, Yasuhisa, Aono, Jun, Hamaguchi, Mika, Takahashi, Kayo, Sakaue, Tomohisa, Inoue, Katsuji, Ikeda, Shuntaro, Yamaguchi, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742050/
https://www.ncbi.nlm.nih.gov/pubmed/34997065
http://dx.doi.org/10.1038/s41598-021-04096-9