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O-ring-induced transverse aortic constriction (OTAC) is a new simple method to develop cardiac hypertrophy and heart failure in mice
Suture-based transverse aortic constriction (TAC) in mice is one of the most frequently used experimental models for cardiac pressure overload-induced heart failure. However, the incidence of heart failure in the conventional TAC depends on the operator’s skill. To optimize and simplify this method,...
Autores principales: | Nakao, Yasuhisa, Aono, Jun, Hamaguchi, Mika, Takahashi, Kayo, Sakaue, Tomohisa, Inoue, Katsuji, Ikeda, Shuntaro, Yamaguchi, Osamu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742050/ https://www.ncbi.nlm.nih.gov/pubmed/34997065 http://dx.doi.org/10.1038/s41598-021-04096-9 |
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