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Identification of missed viruses by metagenomic sequencing of clinical respiratory samples from Kenya

Pneumonia remains a major cause of mortality and morbidity. Most molecular diagnoses of viruses rely on polymerase chain reaction (PCR) assays that however can fail due to primer mismatch. We investigated the performance of routine virus diagnostics in Kilifi, Kenya, using random-primed viral next g...

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Detalles Bibliográficos
Autores principales: Phan, My V. T., Agoti, Charles N., Munywoki, Patrick K., Otieno, Grieven P., Ngama, Mwanajuma, Kellam, Paul, Cotten, Matthew, Nokes, D. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742071/
https://www.ncbi.nlm.nih.gov/pubmed/34997042
http://dx.doi.org/10.1038/s41598-021-03987-1