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Distribution and history of extensional stresses on vWF surrogate molecules in turbulent flow

The configuration of proteins is critical for their biochemical behavior. Mechanical stresses that act on them can affect their behavior leading to the development of decease. The von Willebrand factor (vWF) protein circulating with the blood loses its efficacy when it undergoes non-physiological he...

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Detalles Bibliográficos
Autores principales: Pham, Oanh L., Feher, Samuel E., Nguyen, Quoc T., Papavassiliou, Dimitrios V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742075/
https://www.ncbi.nlm.nih.gov/pubmed/34997036
http://dx.doi.org/10.1038/s41598-021-04034-9