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Experimental aortic aneurysm severity and growth depend on topical elastase concentration and lysyl oxidase inhibition

Abdominal aortic aneurysm (AAA) formation and expansion is highly complex and multifactorial, and the improvement of animal models is an important step to enhance our understanding of AAA pathophysiology. In this study, we explore our ability to influence aneurysm growth in a topical elastase plus β...

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Detalles Bibliográficos
Autores principales: Berman, Alycia G., Romary, Daniel J., Kerr, Katherine E., Gorazd, Natalyn E., Wigand, Morgan M., Patnaik, Sourav S., Finol, Ender A., Cox, Abigail D., Goergen, Craig J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742076/
https://www.ncbi.nlm.nih.gov/pubmed/34997075
http://dx.doi.org/10.1038/s41598-021-04089-8