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Decrease of Pdzrn3 is required for heart maturation and protects against heart failure

Heart failure is the final common stage of most cardiopathies. Cardiomyocytes (CM) connect with others via their extremities by intercalated disk protein complexes. This planar and directional organization of myocytes is crucial for mechanical coupling and anisotropic conduction of the electric sign...

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Detalles Bibliográficos
Autores principales: Pernot, Mathieu, Jaspard-vinassa, Béatrice, Abelanet, Alice, Rubin, Sebastien, Forfar, Isabelle, Jeanningros, Sylvie, Cetran, Laura, Yu, Murielle Han-Yee, Balse, Elise, Hatem, Stéphane, Dufourcq, Pascale, Couffinhal, Thierry, Duplàa, Cécile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742099/
https://www.ncbi.nlm.nih.gov/pubmed/34996942
http://dx.doi.org/10.1038/s41598-021-03795-7