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Decrease of Pdzrn3 is required for heart maturation and protects against heart failure
Heart failure is the final common stage of most cardiopathies. Cardiomyocytes (CM) connect with others via their extremities by intercalated disk protein complexes. This planar and directional organization of myocytes is crucial for mechanical coupling and anisotropic conduction of the electric sign...
Autores principales: | Pernot, Mathieu, Jaspard-vinassa, Béatrice, Abelanet, Alice, Rubin, Sebastien, Forfar, Isabelle, Jeanningros, Sylvie, Cetran, Laura, Yu, Murielle Han-Yee, Balse, Elise, Hatem, Stéphane, Dufourcq, Pascale, Couffinhal, Thierry, Duplàa, Cécile |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742099/ https://www.ncbi.nlm.nih.gov/pubmed/34996942 http://dx.doi.org/10.1038/s41598-021-03795-7 |
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