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Targeting STAT3 prevents bile reflux‐induced oncogenic molecular events linked to hypopharyngeal carcinogenesis
The signal transducer and activator of transcription 3 (STAT3) oncogene is a transcription factor with a central role in head and neck cancer. Hypopharyngeal cells (HCs) exposed to acidic bile present aberrant activation of STAT3, possibly contributing to its oncogenic effect. We hypothesized that S...
Autores principales: | Vageli, Dimitra P., Doukas, Panagiotis G., Siametis, Athanasios, Judson, Benjamin L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742186/ https://www.ncbi.nlm.nih.gov/pubmed/34850540 http://dx.doi.org/10.1111/jcmm.17011 |
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