VLX1570 regulates the proliferation and apoptosis of human lung cancer cells through modulating ER stress and the AKT pathway

The ubiquitin‐proteasome system (UPS) possesses unique functions in tumorigenesis and has great potential for targeting tumours. The effectiveness of inhibitors targeting UPS in solid tumours remains to be studied. We screened a library of inhibitors targeting the ubiquitination system and found the...

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Detalles Bibliográficos
Autores principales: Wang, Juan, Du, Tongde, Lu, Ya, Lv, Yan, Du, Yuxin, Wu, Jianzhong, Ma, Rong, Xu, Chenxin, Feng, Jifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742231/
https://www.ncbi.nlm.nih.gov/pubmed/34854221
http://dx.doi.org/10.1111/jcmm.17053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742231/
https://www.ncbi.nlm.nih.gov/pubmed/34854221
http://dx.doi.org/10.1111/jcmm.17053

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