The Long-Lost Ligase: CRL4(AMBRA1) Regulates the Stability of D-Type Cyclins

D-type cyclins (cyclin D1, D2, and D3, together cyclin D) are central drivers of the cell division cycle and well-described proto-oncoproteins. Rapid turnover of cyclin D is critical for its regulation, but the underlying mechanism has remained a matter of debate. Recently, AMBRA1 was identified as...

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Detalles Bibliográficos
Autores principales: Chaikovsky, Andrea C., Sage, Julien, Pagano, Michele, Simoneschi, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2021
Materias:
DNACB Bits
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742259/
https://www.ncbi.nlm.nih.gov/pubmed/34495753
http://dx.doi.org/10.1089/dna.2021.0659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742259/
https://www.ncbi.nlm.nih.gov/pubmed/34495753
http://dx.doi.org/10.1089/dna.2021.0659

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