Optimized Reversed-Phase Liquid Chromatography/Mass Spectrometry Methods for Intact Protein Analysis and Peptide Mapping of Adeno-Associated Virus Proteins

Recombinant adeno-associated viruses (AAVs) have emerged as the leading gene delivery platform owing to their nonpathogenic nature and long-term gene expression capability. The AAV capsid, in addition to protecting the viral genome, plays an important role in viral infectivity and gene transduction,...

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Detalles Bibliográficos
Autores principales: Zhang, Ximo, Jin, Xiaoying, Liu, Lin, Zhang, Zichuan, Koza, Stephan, Yu, Ying Qing, Chen, Weibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2021
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742267/
https://www.ncbi.nlm.nih.gov/pubmed/34278837
http://dx.doi.org/10.1089/hum.2021.046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742267/
https://www.ncbi.nlm.nih.gov/pubmed/34278837
http://dx.doi.org/10.1089/hum.2021.046

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