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The RNA-binding protein GRSF1 promotes hepatocarcinogenesis via competitively binding to YY1 mRNA with miR-30e-5p

BACKGROUND: Dysregulation of RNA binding protein (RBP) expression has been confirmed to be causally linked with tumorigenesis. The detailed biological effect and underlying mechanisms of the RBP GRSF1 in hepatocellular carcinoma (HCC) remain unclear. METHODS: HCC cells with stable knockdown of GRSF1...

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Detalles Bibliográficos
Autores principales: Han, Lili, Huang, Chen, Wang, Xiaofei, Tong, Dongdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742353/
https://www.ncbi.nlm.nih.gov/pubmed/34998399
http://dx.doi.org/10.1186/s13046-021-02217-w