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The industrial solvent 1,4-dioxane causes hyperalgesia by targeting capsaicin receptor TRPV1
BACKGROUND: The synthetic chemical 1,4-dioxane is used as industrial solvent, food, and care product additive. 1,4-Dioxane has been noted to influence the nervous system in long-term animal experiments and in humans, but the molecular mechanisms underlying its effects on animals were not previously...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742357/ https://www.ncbi.nlm.nih.gov/pubmed/34996439 http://dx.doi.org/10.1186/s12915-021-01211-0 |