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The industrial solvent 1,4-dioxane causes hyperalgesia by targeting capsaicin receptor TRPV1

BACKGROUND: The synthetic chemical 1,4-dioxane is used as industrial solvent, food, and care product additive. 1,4-Dioxane has been noted to influence the nervous system in long-term animal experiments and in humans, but the molecular mechanisms underlying its effects on animals were not previously...

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Detalles Bibliográficos
Autores principales: Mo, Xiaoyi, Liu, Qiang, Gao, Luna, Xie, Chang, Wei, Xin, Pang, Peiyuan, Tian, Quan, Gao, Yue, Zhang, Youjing, Wang, Yuanyuan, Xiong, Tianchen, Zhong, Bo, Li, Dongdong, Yao, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742357/
https://www.ncbi.nlm.nih.gov/pubmed/34996439
http://dx.doi.org/10.1186/s12915-021-01211-0