Integrative analysis of 3604 GWAS reveals multiple novel cell type-specific regulatory associations

BACKGROUND: Genome-wide association study (GWAS) single nucleotide polymorphisms (SNPs) are known to preferentially co-locate to active regulatory elements in tissues and cell types relevant to disease aetiology. Further characterisation of associated cell type-specific regulation can broaden our un...

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Detalles Bibliográficos
Autores principales: Breeze, Charles E., Haugen, Eric, Reynolds, Alex, Teschendorff, Andrew, van Dongen, Jenny, Lan, Qing, Rothman, Nathaniel, Bourque, Guillaume, Dunham, Ian, Beck, Stephan, Stamatoyannopoulos, John, Franceschini, Nora, Berndt, Sonja I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742386/
https://www.ncbi.nlm.nih.gov/pubmed/34996498
http://dx.doi.org/10.1186/s13059-021-02560-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742386/
https://www.ncbi.nlm.nih.gov/pubmed/34996498
http://dx.doi.org/10.1186/s13059-021-02560-3

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