Activation of α7 Nicotinic Acetylcholine Receptor by its Selective Agonist Improved Learning and Memory of Amyloid Precursor Protein/Presenilin 1 (APP/PS1) Mice via the Nrf2/HO-1 Pathway

BACKGROUND: To reveal the mechanism underlying the effect of α7 nicotinic acetylcholine receptor (nAChR) on neurodegeneration in Alzheimer disease (AD), the influence of the receptor on recognition in APP/PS1 mice was evaluated by using its selective agonist (PNU-282987). MATERIAL/METHODS: APP/PS1 a...

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Detalles Bibliográficos
Autores principales: Cao, Kun, Xiang, Jie, Dong, Yang-Ting, Xu, Yi, Guan, Zhi-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2022
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742434/
https://www.ncbi.nlm.nih.gov/pubmed/34980874
http://dx.doi.org/10.12659/MSM.933978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742434/
https://www.ncbi.nlm.nih.gov/pubmed/34980874
http://dx.doi.org/10.12659/MSM.933978

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