CRISPR/Cas9-mediated gene knockout and interallelic gene conversion in human induced pluripotent stem cells using non-integrative bacteriophage-chimeric retrovirus-like particles

BACKGROUND: The application of CRISPR/Cas9 technology in human induced pluripotent stem cells (hiPSC) holds tremendous potential for basic research and cell-based gene therapy. However, the fulfillment of these promises relies on the capacity to efficiently deliver exogenous nucleic acids and harnes...

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Detalles Bibliográficos
Autores principales: Mianné, Joffrey, Nasri, Amel, Van, Chloé Nguyen, Bourguignon, Chloé, Fieldès, Mathieu, Ahmed, Engi, Duthoit, Christine, Martin, Nicolas, Parrinello, Hugues, Louis, Anaïs, Iché, Alexandra, Gayon, Régis, Samain, Florine, Lamouroux, Lucille, Bouillé, Pascale, Bourdin, Arnaud, Assou, Said, De Vos, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742436/
https://www.ncbi.nlm.nih.gov/pubmed/34996449
http://dx.doi.org/10.1186/s12915-021-01214-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742436/
https://www.ncbi.nlm.nih.gov/pubmed/34996449
http://dx.doi.org/10.1186/s12915-021-01214-x

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