Evolutionary analyses of the gasdermin family suggest conserved roles in infection response despite loss of pore-forming functionality

BACKGROUND: Gasdermins are ancient (>500million-years-ago) proteins, constituting a family of pore-forming proteins that allow the release of intracellular content including proinflammatory cytokines. Despite their importance in the immune response, and although gasdermin and gasdermin-like genes...

Descripción completa

Detalles Bibliográficos
Autores principales: Angosto-Bazarra, Diego, Alarcón-Vila, Cristina, Hurtado-Navarro, Laura, Baños, María C., Rivers-Auty, Jack, Pelegrín, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742441/
https://www.ncbi.nlm.nih.gov/pubmed/34996441
http://dx.doi.org/10.1186/s12915-021-01220-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742441/
https://www.ncbi.nlm.nih.gov/pubmed/34996441
http://dx.doi.org/10.1186/s12915-021-01220-z

Ejemplares similares