Leveraging pleiotropic association using sparse group variable selection in genomics data

BACKGROUND: Genome-wide association studies (GWAS) have identified genetic variants associated with multiple complex diseases. We can leverage this phenomenon, known as pleiotropy, to integrate multiple data sources in a joint analysis. Often integrating additional information such as gene pathway k...

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Detalles Bibliográficos
Autores principales: Sutton, Matthew, Sugier, Pierre-Emmanuel, Truong, Therese, Liquet, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742466/
https://www.ncbi.nlm.nih.gov/pubmed/34996381
http://dx.doi.org/10.1186/s12874-021-01491-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742466/
https://www.ncbi.nlm.nih.gov/pubmed/34996381
http://dx.doi.org/10.1186/s12874-021-01491-8

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