Axonal Protection by Netarsudil, a ROCK Inhibitor, Is Linked to an AMPK-Autophagy Pathway in TNF-Induced Optic Nerve Degeneration

PURPOSE: Netarsudil, a Rho kinase inhibitor with norepinephrine transport inhibitory effect, lowers intraocular pressure, however, its effect on axon damage remains to be elucidated. The aim of the current study was to investigate the effect of netarsudil on TNF-induced axon loss and to examine whet...

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Detalles Bibliográficos
Autores principales: Kitaoka, Yasushi, Sase, Kana, Tsukahara, Chihiro, Fujita, Naoki, Arizono, Ibuki, Kogo, Jiro, Tokuda, Naoto, Takagi, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Eye Movements, Strabismus, Amblyopia and Neuro-Ophthalmology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742515/
https://www.ncbi.nlm.nih.gov/pubmed/34982146
http://dx.doi.org/10.1167/iovs.63.1.4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742515/
https://www.ncbi.nlm.nih.gov/pubmed/34982146
http://dx.doi.org/10.1167/iovs.63.1.4

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