Translational Modeling of Chloroquine and Hydroxychloroquine Dosimetry in Human Airways for Treating Viral Respiratory Infections

PURPOSE: Chloroquine and hydroxychloroquine are effective against respiratory viruses in vitro. However, they lack antiviral efficacy upon oral administration. Translation of in vitro to in vivo exposure is necessary for understanding the disconnect between the two to develop effective therapeutic s...

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Detalles Bibliográficos
Autores principales: Kolli, Aditya R., Calvino-Martin, Florian, Hoeng, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742698/
https://www.ncbi.nlm.nih.gov/pubmed/35000036
http://dx.doi.org/10.1007/s11095-021-03152-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742698/
https://www.ncbi.nlm.nih.gov/pubmed/35000036
http://dx.doi.org/10.1007/s11095-021-03152-3

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