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Necrotic debris and STING exert therapeutically relevant effects on tumor cholesterol homeostasis

Malignant tumors commonly display necrosis, which invariably triggers an inflammatory response that supports tumor growth. However, the effect on tumor cells of necrotic debris, or damage-associated molecular patterns (DAMPs) released by dying cells is unknown. Here, we addressed the effect of DAMPs...

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Detalles Bibliográficos
Autores principales: Katakam, Sampath, Anand, Santosh, Martin, Patricia, Riggi, Nicolo, Stamenkovic, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742871/
https://www.ncbi.nlm.nih.gov/pubmed/34983824
http://dx.doi.org/10.26508/lsa.202101256