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Necrotic debris and STING exert therapeutically relevant effects on tumor cholesterol homeostasis
Malignant tumors commonly display necrosis, which invariably triggers an inflammatory response that supports tumor growth. However, the effect on tumor cells of necrotic debris, or damage-associated molecular patterns (DAMPs) released by dying cells is unknown. Here, we addressed the effect of DAMPs...
Autores principales: | Katakam, Sampath, Anand, Santosh, Martin, Patricia, Riggi, Nicolo, Stamenkovic, Ivan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742871/ https://www.ncbi.nlm.nih.gov/pubmed/34983824 http://dx.doi.org/10.26508/lsa.202101256 |
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