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Functional signaling test identifies HER2 negative breast cancer patients who may benefit from c-Met and pan-HER combination therapy

BACKGROUND: Research is revealing the complex coordination between cell signaling systems as they adapt to genetic and epigenetic changes. Tools to uncover these highly complex functional linkages will play an important role in advancing more efficacious disease treatments. Current tumor cell signal...

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Detalles Bibliográficos
Autores principales: MacNeil, Ian A., Khan, Salmaan A., Sen, Adrish, Soltani, Sajjad M., Burns, David J., Sullivan, Brian F., Laing, Lance G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8742957/
https://www.ncbi.nlm.nih.gov/pubmed/34998412
http://dx.doi.org/10.1186/s12964-021-00798-9