Myeloid cell-mediated targeting of LIF to dystrophic muscle causes transient increases in muscle fiber lesions by disrupting the recruitment and dispersion of macrophages in muscle

Leukemia inhibitory factor (LIF) can influence development by increasing cell proliferation and inhibiting differentiation. Because of its potency for expanding stem cell populations, delivery of exogenous LIF to diseased tissue could have therapeutic value. However, systemic elevations of LIF can h...

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Detalles Bibliográficos
Autores principales: Flores, Ivan, Welc, Steven S, Wehling-Henricks, Michelle, Tidball, James G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
General Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743000/
https://www.ncbi.nlm.nih.gov/pubmed/34392367
http://dx.doi.org/10.1093/hmg/ddab230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743000/
https://www.ncbi.nlm.nih.gov/pubmed/34392367
http://dx.doi.org/10.1093/hmg/ddab230

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