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A new glimpse on the active site of SARS-CoV-2 3CLpro, coupled with drug repurposing study

ABSTRACT: Coronavirus disease 2019 (COVID-19) is caused by novel severe acute respiratory syndrome coronavirus (SARS-CoV-2). Its main protease, 3C-like protease (3CLpro), is an attractive target for drug design, due to its importance in virus replication. The analysis of the radial distribution func...

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Detalles Bibliográficos
Autores principales: Novak, Jurica, Potemkin, Vladimir A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743077/
https://www.ncbi.nlm.nih.gov/pubmed/35001230
http://dx.doi.org/10.1007/s11030-021-10355-8