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Fragment-based exploration of the 14-3-3/Amot-p130 interface
The modulation of protein-protein interactions (PPIs) has developed into a well-established field of drug discovery. Despite the advances achieved in the field, many PPIs are still deemed as ‘undruggable’ targets and the design of PPIs stabilizers remains a significant challenge. The application of...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743172/ https://www.ncbi.nlm.nih.gov/pubmed/35036934 http://dx.doi.org/10.1016/j.crstbi.2021.12.003 |