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Fragment-based exploration of the 14-3-3/Amot-p130 interface

The modulation of protein-protein interactions (PPIs) has developed into a well-established field of drug discovery. Despite the advances achieved in the field, many PPIs are still deemed as ‘undruggable’ targets and the design of PPIs stabilizers remains a significant challenge. The application of...

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Detalles Bibliográficos
Autores principales: Centorrino, Federica, Andlovic, Blaž, Cossar, Peter, Brunsveld, Luc, Ottmann, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743172/
https://www.ncbi.nlm.nih.gov/pubmed/35036934
http://dx.doi.org/10.1016/j.crstbi.2021.12.003