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Quantification of the trans-synaptic partners neurexin-neuroligin in CSF of neurodegenerative diseases by parallel reaction monitoring mass spectrometry

BACKGROUND: Synaptic proteins are increasingly studied as biomarkers for synaptic dysfunction and loss, which are early and central events in Alzheimer's disease (AD) and strongly correlate with the degree of cognitive decline. In this study, we specifically investigated the synaptic binding pa...

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Detalles Bibliográficos
Autores principales: Camporesi, Elena, Nilsson, Johanna, Vrillon, Agathe, Cognat, Emmanuel, Hourregue, Claire, Zetterberg, Henrik, Blennow, Kaj, Becker, Bruno, Brinkmalm, Ann, Paquet, Claire, Brinkmalm, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743209/
https://www.ncbi.nlm.nih.gov/pubmed/34990894
http://dx.doi.org/10.1016/j.ebiom.2021.103793