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Quantification of the trans-synaptic partners neurexin-neuroligin in CSF of neurodegenerative diseases by parallel reaction monitoring mass spectrometry
BACKGROUND: Synaptic proteins are increasingly studied as biomarkers for synaptic dysfunction and loss, which are early and central events in Alzheimer's disease (AD) and strongly correlate with the degree of cognitive decline. In this study, we specifically investigated the synaptic binding pa...
Autores principales: | Camporesi, Elena, Nilsson, Johanna, Vrillon, Agathe, Cognat, Emmanuel, Hourregue, Claire, Zetterberg, Henrik, Blennow, Kaj, Becker, Bruno, Brinkmalm, Ann, Paquet, Claire, Brinkmalm, Gunnar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8743209/ https://www.ncbi.nlm.nih.gov/pubmed/34990894 http://dx.doi.org/10.1016/j.ebiom.2021.103793 |
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